Vuyo is co-founder of Krutham and a director of the company. He is chairman of Empowerdex which he founded with Chia-Chao Wu. He is a director of various companies. He is a commissioner on the Davis tax review committee, having been appointed by the minister of finance. He was nominated as a Young Global Leader by the 2009 World Economic Forum.
Vuyo holds a BCom from Wits University and is a chartered accountant.